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1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID

1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Suppliers list
Company Name: Accela ChemBio Inc.
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Products Intro: Product Name:1-Cbz-azetidine-3-carboxylic Acid
CAS:97628-92-7
Purity:>=95% Package:1g;5g;10g;25g;100g;500g
Company Name: Chengdu Pukang Biotechnology Co., Ltd
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Products Intro: Product Name:1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID
CAS:97628-92-7
Purity:98% Package:1g;USD
Company Name: Alchem Pharmtech,Inc.
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Products Intro: Product Name:1-Cbz-Azetidine-3-carboxylic acid
CAS:97628-92-7
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-20636
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
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Products Intro: Product Name:1-benzyloxycarbonylazetidine-3-carboxylic acid
CAS:97628-92-7
Purity:0.97 Package:1KG;25KG
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Products Intro: Product Name:1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID
CAS:97628-92-7
Purity:95%-99% Package:1KG;9.2USD

1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID manufacturers

1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Basic information
Product Name:1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID
Synonyms:1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID;1-Cbz-azetidine-3-carboxylic acid;N-Cbz-azetidine-3-carboxylic acid;1-benzyloxycarbonyl-3-azetidinecarboxylic acid;1-Cbz-azetidine-3-carboxy...;CBZ-AZETIDINE-3-CARBOXYLIC ACID;N-(Benzyloxycarbonyl)azetidine-3-carboxylic acid, 95%;Azetidine-1,3-dicarboxylic acid 1-benzyl ester
CAS:97628-92-7
MF:C12H13NO4
MW:235.24
EINECS:
Product Categories:
Mol File:97628-92-7.mol
1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Structure
1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Chemical Properties
Boiling point 421.2±45.0 °C(Predicted)
density 1.362
storage temp. 2-8°C
pka4.19±0.20(Predicted)
form Solid
color White to off-white
Safety Information
HazardClass IRRITANT
HS Code 2933998090
MSDS Information
1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Usage And Synthesis
Uses1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
IC 50Non-cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. DOI:10.1038/nrd.2016.268
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Tag:1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID(97628-92-7) Related Product Information
Cbz-S-3-Aminoisobutyric acid BENZYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE 1-(BENZYLOXYCARBONYL) AZETIDINE-3-CARBOXYLIC ACID

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